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1

Phase III randomized trial comparing 5-fluorouracil and oxaliplatin with or without docetaxel in first-line advanced gastric cancer chemotherapy (GASTFOX study)

Zaanan, Aziz, Samalin, Emmanuelle, Aparicio, Thomas, Bouche, Olivier, Laurent-Puig, Pierre, Manfredi, Sylvain, Michel, Pierre, Monterymard, Carole, Moreau, Marie, Rougier, Philippe, Tougeron, David, T

Journal:

Digestive and Liver Disease

Year:

2018

Language:

english

File:

PDF, 339 KB

english, 2018

2

Nouveaux marqueurs tumoraux

Pierre Laurent-Puig

Journal:

Revue Française des Laboratoires

Year:

2001

File:

PDF, 232 KB

2001

3

Characterization of a frequent polymorphism in the coding sequence of the Tp53 gene in colonic cancer patients and a control population

Sylviane Olschwang, Pierre Laurent-Puig, Anne Vassal, Rémy-J. Salmon, Gilles Thomas

Journal:

Year:

1991

Language:

english

File:

PDF, 207 KB

english, 1991

4

Molecular predictors of response to EGFR antibodies in colorectal cancer

Astrid Lièvre, Pierre Laurent-Puig

Journal:

Current Colorectal Cancer Reports

Year:

2008

Language:

english

File:

PDF, 331 KB

english, 2008

5

Molecular predictors of response to EGFR antibodies in colorectal cancer

Astrid Lièvre, Pierre Laurent-Puig

Journal:

Current Colorectal Cancer Reports

Year:

2009

Language:

english

File:

PDF, 388 KB

english, 2009

6

DeltaN TP63 reactivation, epithelial phenotype maintenance, and survival in lung squamous cell carcinoma

Karine Pallier, Aurélie Cazes, Laila El Khattabi, Cristina Lecchi, Marine Desroches, Claire Danel, Marc Riquet, Elizabeth Fabre-Guillevin, Pierre Laurent-Puig, Hélène Blons

Journal:

Year:

2012

Language:

english

File:

PDF, 646 KB

english, 2012

7

Restriction of ocular fundus lesions to a specific subgroup of APC mutations in adenomatous polyposis coli patients

Sylviane Olschwang, Anne Tiret, Pierre Laurent-Puig, Martine Muleris, Rolland Parc, Gilles Thomas

Journal:

Year:

1993

Language:

english

File:

PDF, 1.50 MB

english, 1993

8

Prognostic relevance of p53 mutation in colorectal carcinoma

Hamelin, Richard, Laurent-Puig, Pierre, Thomas, Gilles, Asselain, Bernard

Journal:

Gastroenterology

Year:

1994

Language:

english

File:

PDF, 172 KB

english, 1994

9

STRATEGIC-1: A multiple-lines, randomized, open-label GERCOR phase III study in patients with unresectable wild-type RAS metastatic colorectal cancer

Chibaudel, Benoist, Bonnetain, Franck, Tournigand, Christophe, de Larauze, Marine Hug, de Gramont, Armand, Laurent-Puig, Pierre, Paget, Jérôme, Hadengue, Alexandra, Notelet, Dominique, Benetkiewicz, M

Journal:

Year:

2015

Language:

english

File:

PDF, 845 KB

english, 2015

10

Place du NGS (Next Generation Sequencing) et de l’ADN tumoral circulant dans le testing moléculaire des cancers bronchiques

Pécuchet, Nicolas, Legras, Antoine, Laurent-Puig, Pierre, Blons, Hélène

Journal:

Annales de Pathologie

Year:

2016

Language:

french

File:

PDF, 3.14 MB

french, 2016

11

Association of p53 mutations with short survival in colorectal cancer

Hamelin, Richard, Laurent-Puig, Pierre, Olschwang, Sylviane, Jego, Nathalie, Asselain, Bernard, Remvikos, Yorghos, Girodet, Jacques, Salmon, Remi J., Thomas, Gilles

Journal:

Gastroenterology

Year:

1994

Language:

english

File:

PDF, 1.20 MB

english, 1994

12

Targeting c-MET in gastrointestinal tumours: rationale, opportunities and challenges

Bradley, Conor A., Salto-Tellez, Manuel, Laurent-Puig, Pierre, Bardelli, Alberto, Rolfo, Christian, Tabernero, Josep, Khawaja, Hajrah A., Lawler, Mark, Johnston, Patrick G., Van Schaeybroeck, Sandra

Journal:

Nature Reviews Clinical Oncology (formerly Nature Clinical Practice Oncology)

Year:

2017

Language:

english

File:

PDF, 1.02 MB

english, 2017

13

Droplet-based digital PCR and next generation sequencing for monitoring circulating tumor DNA: a cancer diagnostic perspective

POSTEL, Mathilde, ROOSEN, Alice, LAURENT-PUIG, Pierre, TALY, Valerie, WANG-RENAULT, Shu-Fang

Journal:

Expert Review of Molecular Diagnostics

Year:

2017

Language:

english

File:

PDF, 1.41 MB

english, 2017

14

PCR digitale en micro-compartiments

Perez-Toralla, Karla, Pekin, Deniz, Bartolo, Jean-François, Garlan, Fanny, Nizard, Philippe, Laurent-Puig, Pierre, Baret, Jean-Christophe, Taly, Valérie

Journal:

médecine/sciences

Year:

2015

Language:

french

File:

PDF, 3.61 MB

french, 2015

15

Prognostic influence of clinicopathologic features, DNA-ploidy, CD44H and p53 expression in a large series of resected hepatocellular carcinoma in france

Benoît Terris, Pierre Laurent-Puig, Jacques Belghiti, Claude Degott, Dominique Hénin, Jean-François Fléjou

Journal:

International Journal of Cancer

Year:

1997

Language:

english

File:

PDF, 170 KB

english, 1997

16

Somatically acquired genetic alterations in flat colorectal neoplasias

Sylviane Olschwang, Premysl Slezak, Maud Roze, Edgar Jaramillo, Hiroshi Nakano, Koichi Koizumi, Carlos A. Rubio, Pierre Laurent-Puig, Gilles Thomas

Journal:

International Journal of Cancer

Year:

1998

Language:

english

File:

PDF, 385 KB

english, 1998

17

Mutational analysis of the PTEN gene in gliomas: Molecular and pathological correlations

Xiao-Ping Zhou, You-Jun Li, Khê Hoang-Xuan, Pierre Laurent-Puig, Karima Mokhtari, Michel Longy, Marc Sanson, Jean-Yves Delattre, Gilles Thomas, Richard Hamelin

Journal:

International Journal of Cancer

Year:

1999

Language:

english

File:

PDF, 97 KB

english, 1999

18

No evidence for germline PTEN mutations in families with breast and brain tumours

Anthony Laugé, Céline Lefebvre, Pierre Laurent-Puig, Virginie Caux, Sophie Gad, Charis Eng, Michel Longy, Dominique Stoppa-Lyonnet

Journal:

International Journal of Cancer

Year:

1999

Language:

english

File:

PDF, 117 KB

english, 1999

19

Microsatellite analysis and response to chemotherapy in head-and-neck squamous-cell carcinoma

Hélène Blons, Arnauld Cabelguenne, Françoise Carnot, Ollivier Laccourreye, Isabelle de Waziers, Richard Hamelin, Daniel Brasnu, Philippe Beaune, Pierre Laurent-Puig

Journal:

International Journal of Cancer

Year:

1999

Language:

english

File:

PDF, 144 KB

english, 1999

20

Germline mutation profile of the VHL gene in von Hippel-Lindau disease and in sporadic hemangioblastoma

Sylviane Olschwang, Stéphane Richard, Cécile Boisson, Sophie Giraud, Pierre Laurent-Puig, François Resche, Gilles Thomas

Journal:

Year:

1998

Language:

english

File:

PDF, 252 KB

english, 1998

21

Deletion mapping of the tumor suppressor locus involved in colorectal cancer on chromosome band 8p21

Florence Lerebours, Sylviane Olschwang, Bénédicte Thuille, Annette Schmitz, Pierre Fouchet, Pierre Laurent-Puig, Françoise Boman, Jean-François Fléjou, Geneviève Monges, François Paraf, Pierre Bedossa

Journal:

Genes, Chromosomes and Cancer

Year:

1999

Language:

english

File:

PDF, 144 KB

english, 1999

22

Frequent allelic loss at chromosome 3p distinct from genetic alterations of the 8-oxoguanine DNA glycosylase 1 gene in head and neck cancer

Hélène Blons, J. Pablo Radicella, Ollivier Laccourreye, Daniel Brasnu, Philippe Beaune, Serge Boiteux, Pierre Laurent-Puig

Journal:

Molecular Carcinogenesis

Year:

1999

Language:

english

File:

PDF, 170 KB

english, 1999

23

Determination of microsatellite instability, p53 and K-RAS mutations in hepatic metastases from patients with colorectal cancer: Relationship with response to 5-fluorouracil and survival

Christophe Rosty, Maurice Chazal, Marie-Christine Etienne, Christian Letoublon, André Bourgeon, Jean-Robert Delpero, Denis Pezet, Philippe Beaune, Pierre Laurent-Puig, Gérard Milano

Journal:

International Journal of Cancer

Year:

2001

Language:

english

File:

PDF, 80 KB

english, 2001

24

Linkage analyses of chromosome 6 loci, including HLA, in familial aggregations of Crohn disease

Jean Pierre Hugot, Pierre Laurent-Puig, Corine Gower-Rousseau, Sophie Caillat-Zucman, Laurent Beaugerie, Jean-Louis Dupas, André Van Gossum, Catherine Bonaïti-Pellie, Antoine Cortot, Gilles Thomas, G.

Journal:

American Journal of Medical Genetics Part A

Year:

1994

Language:

english

File:

PDF, 695 KB

english, 1994

25

High resolution genetic map of the adenomatous polyposis coli gene (APC) region

Sylviane Olschwang, Pierre Laurent-Puig, Thomas Melot, Bénédicte Thuille, Dr. Gilles Thomas

Journal:

American Journal of Medical Genetics Part A

Year:

1995

Language:

english

File:

PDF, 833 KB

english, 1995

26

Screening for germ-line mutations in the NF2 Gene

Philippe Mérel, Khé Hoang-Xuan, Marc Sanson, Emilia Bijlsma, Guy Rouleau, Pierre Laurent-Puig, Stephan Pulst, Michael Baser, Gilbert Lenoir, Jean Marc Sterkers, Jacques Philippon, François Resche, Vic

Journal:

Genes, Chromosomes and Cancer

Year:

1995

Language:

english

File:

PDF, 876 KB

english, 1995

27

Overexpression of p53: A rare event in a large series of white patients with hepatocellular carcinoma

Pierre Laurent-Puig, Jean-François Flejou, Monique Fabre, Pierre Bedossa, Jacques Belghiti, François Gayral, Dominique Franco

Journal:

Year:

1992

Language:

english

File:

PDF, 631 KB

english, 1992

28

TP53 and head and neck neoplasms

Hélène Blons, Pierre Laurent-Puig

Journal:

Year:

2003

Language:

english

File:

PDF, 116 KB

english, 2003

29

Prognostic value of P53 mutations in rectal carcinoma

Christine Rebischung, Jean-Pierre Gérard, Jacqueline Gayet, Gilles Thomas, Richard Hamelin, Pierre Laurent-Puig

Journal:

International Journal of Cancer

Year:

2002

Language:

english

File:

PDF, 79 KB

english, 2002

30

Detection of free-circulating tumor-associated DNA in plasma of colorectal cancer patients and its association with prognosis

Thierry Lecomte, Anne Berger, Franck Zinzindohoué, Stéphanie Micard, Bruno Landi, Hélène Blons, Philippe Beaune, Paul-Henri Cugnenc, Pierre Laurent-Puig

Journal:

International Journal of Cancer

Year:

2002

Language:

english

File:

PDF, 146 KB

english, 2002

31

Glutathione-associated enzymes in head and neck squamous cell carcinoma and response to cisplatin-based neoadjuvant chemotherapy

Arnauld Cabelguenne, Marie-Anne Loriot, Isabelle Stucker, Hèléne Blons, Elisabeth Koum-Besson, Daniel Brasnu, Philipe Beaune, Ollivier Laccourreye, Pierre Laurent-Puig, Isabelle De Waziers

Journal:

International Journal of Cancer

Year:

2001

Language:

english

File:

PDF, 75 KB

english, 2001

32

Impact of GSTT1, GSTM1, GSTP1 and NAT2 genotypes on KRAS2 and TP53 gene mutations in colorectal cancer

Jean-Marc Ferraz, Franck Zinzindohoué, Thierry Lecomte, Paul-Henri Cugnenc, Marie-Anne Loriot, Philippe Beaune, Isabelle Stücker, Anne Berger, Pierre Laurent-Puig

Journal:

International Journal of Cancer

Year:

2004

Language:

english

File:

PDF, 92 KB

english, 2004

33

Evidence of heterogeneity within colorectal liver metastases for allelic losses, mRNA level expression and in vitro response to chemotherapeutic agents

Nicolas Goasguen, Cecile de Chaisemartin, Antoine Brouquet, Catherine Julié, Gregoire P. Prevost, Pierre Laurent-Puig, Christophe Penna

Journal:

International Journal of Cancer

Year:

2010

Language:

english

File:

PDF, 619 KB

english, 2010

34

Butyrate elicits a metabolic switch in human colon cancer cells by targeting the pyruvate dehydrogenase complex

Jean-Marc Blouin, Graziella Penot, Martine Collinet, Magali Nacfer, Claude Forest, Pierre Laurent-Puig, Xavier Coumoul, Robert Barouki, Chantal Benelli, Sylvie Bortoli

Journal:

International Journal of Cancer

Year:

2011

Language:

english

File:

PDF, 690 KB

english, 2011

35

No somatic genetic change in the paxillin gene in nonsmall-cell lung cancer

Karine Pallier, Anne-Marie Houllier, Delphine Le Corre, Aurélie Cazes, Pierre Laurent-Puig, Hélène Blons

Journal:

Molecular Carcinogenesis

Year:

2009

Language:

english

File:

PDF, 91 KB

english, 2009

36

Genome wide SNP comparative analysis between EGFR and KRAS mutated NSCLC and characterization of two models of oncogenic cooperation in non-small cell lung carcinoma

Hélène Blons, Karine Pallier, Delphine Le Corre, Claire Danel, Maxime Tremblay-Gravel, Claude Houdayer, Elizabeth Fabre-Guillevin, Marc Riquet, Philippe Dessen, Pierre Laurent-Puig

Journal:

BMC Medical Genomics

Year:

2008

Language:

english

File:

PDF, 620 KB

english, 2008

37

Detection by DGGE of a new polymorphism closely linked to the adenomatous polyposis coli region

Sylviane Olschwang, Richard Fabre, Pierre Laurent-Puig, Anne Vassal, Bernard Hamelin, Yusuke Nakamura, Gilles Thomas

Journal:

Year:

1992

Language:

english

File:

PDF, 309 KB

english, 1992

38

Effect of cytochromeP450 2C19genotype on voriconazole exposure in cystic fibrosis lung transplant patients

Maud Berge, Romain Guillemain, David A. Trégouet, Catherine Amrein, Veronique Boussaud, Patrick Chevalier, Agnes Lillo-Lelouet, Christine Le Beller, Pierre Laurent-Puig, Philippe H. Beaune, Eliane M.

Journal:

European Journal of Clinical Pharmacology

Year:

2011

Language:

english

File:

PDF, 266 KB

english, 2011

39

Microsatellite instability analysis in uterine cavity washings as a screening tool for endometrial cancer in Lynch syndrome

Julie Bouquier, Hélène Blons, Céline Narjoz, Fabrice Lécuru, Pierre Laurent-Puig, Anne-Sophie Bats

Journal:

Familial Cancer

Year:

2011

Language:

english

File:

PDF, 127 KB

english, 2011

40

Incidence ofKRASstatus in ongoing adjuvant trials in colon cancer

Julien Taieb, Pierre Laurent-Puig, Steven Alberts

Journal:

Current Colorectal Cancer Reports

Year:

2009

Language:

english

File:

PDF, 368 KB

english, 2009

41

Microsatellite Status and Adjuvant Chemotherapy in Patients with Stage II Colon Cancer

Jean-Baptiste Bachet, Pierre Laurent-Puig, Aimery de Gramont, Thierry André

Journal:

Current Colorectal Cancer Reports

Year:

2010

Language:

english

File:

PDF, 183 KB

english, 2010

42

Mapping of a susceptibility locus for Crohn's disease on chromosome 16

Hugot, Jean-Pierre, Laurent-Puig, Pierre, Gower-Rousseau, Corine, Olson, Jane M., Lee, John C., Beaugerie, Laurent, Naom, Isam, Dupas, Jean-Louis, Van Gossum, André, Orholm, Marianne

Journal:

Year:

1996

File:

PDF, 705 KB

1996

43

Genetics: Predictive value of KRAS mutations in chemoresistant CRC

Lièvre, Astrid, Laurent-Puig, Pierre

Journal:

Nature Reviews Clinical Oncology (formerly Nature Clinical Practice Oncology)

Year:

2009

Language:

english

File:

PDF, 93 KB

english, 2009

44

Beta-catenin mutations in hepatocellular carcinoma correlate with a low rate of loss of heterozygosity

Legoix, Patricia, Bluteau, Olivier, Bayer, Jan, Perret, Christine, Balabaud, Charles, Belghiti, Jacques, Franco, Dominique, Thomas, Gilles, Laurent-Puig, Pierre, Zucman-Rossi, Jessica

Journal:

Year:

1999

Language:

english

File:

PDF, 99 KB

english, 1999

45

Specific association between alcohol intake, high grade of differentiation and 4q34-q35 deletions in hepatocellular carcinomas identified by high resolution allelotyping

Bluteau, Olivier, Beaudoin, Jean-Christophe, Pasturaud, Patricia, Belghiti, Jacques, Franco, Dominique, Bioulac-Sage, Paulette, Laurent-Puig, Pierre, Zucman-Rossi, Jessica

Journal:

Year:

2002

Language:

english

File:

PDF, 660 KB

english, 2002

46

Delineation and candidate gene mutation screening of the 18q22 minimal region of deletion in head and neck squamous cell carcinoma

Blons, Hélène, Laccourreye, Ollivier, Houllier, Anne-Marie, Carnot, Françoise, Brasnu, Daniel, Beaune, Philippe, Zucman-Rossi, Jessica, Laurent-Puig, Pierre

Journal:

Year:

2002

Language:

english

File:

PDF, 402 KB

english, 2002

47

Mutation of TCF1 encoding hepatocyte nuclear factor 1α in gynecological cancer

Rebouissou, Sandra, Rosty, Christophe, Lecuru, Fabrice, Boisselier, Sophie, Bui, Hung, Frere-Belfa, Marie-Aude Le, Sastre, Xavier, Laurent-Puig, Pierre, Zucman-Rossi, Jessica

Journal:

Year:

2004

Language:

english

File:

PDF, 201 KB

english, 2004

48

Absence of mutation in the putative tumor-suppressor gene KLF6 in colorectal cancers

Lièvre, Astrid, Landi, Bruno, Côté, Jean-François, Veyrie, Nicolas, Zucman-Rossi, Jessica, Berger, Anne, Laurent-Puig, Pierre

Journal:

Year:

2005

Language:

english

File:

PDF, 147 KB

english, 2005

49

Genetic alterations in hepatocellular adenomas

Paulette Bioulac-Sage, Pierre Laurent-Puig, Charles Balabaud, Jessica Zucman-Rossi

Journal:

Year:

2003

Language:

english

File:

PDF, 41 KB

english, 2003

50

Association between Parkinson's disease and the HLA-DRB1 locus

Ismaïl Ahmed, Ryad Tamouza, Marc Delord, Rajagopal Krishnamoorthy, Christophe Tzourio, Claire Mulot, Magali Nacfer, Jean-Charles Lambert, Philippe Beaune, Pierre Laurent-Puig, Marie-Anne Loriot, Domin

Journal:

Movement Disorders

Year:

2012

Language:

english

File:

PDF, 887 KB

english, 2012